Lilly, Novo Nordisk and Sanofi slash prices of insulin in the US

Biosimilares/General | Posted 23/03/2023 post-comment0 Post your comment

In March 2023, major insulin manufacturers Eli Lilly (Lilly), Novo Nordisk and Sanofi announced price reductions of 70%, 75% and 78% respectively, for their most commonly prescribed insulins in the US, starting from first quarter of 2023 for Lilly and from 1 January 2024 for Novo Nordisk and Sanofi. The three companies control over 90% of the global insulin market. 

Insulin 1 V13C03

In addition, Lilly will be expanding its Insulin Value Program that caps patient out-of-pocket costs at US$35 or less per month, announced on 1 March 2023.

Lilly is taking three key actions to make it more affordable for patients to access Lilly insulin products starting in early 2023:

  • In the first quarter of 2023, Lilly is cutting the list price of Humalog (insulin lispro injection) 100 units/mL1, their most frequently prescribed insulin, and Humulin® (insulin human) injection 100 units/mL2 by 70%.
  • From 1 April 2023, Lilly is launching Rezvoglar (insulin glargine-aglr) injection [1], a basal insulin interchangeable biosimilar of the Lantus (insulin glargine) injection, for US$92 per five pack of KwikPens (78% discount relative to Lantus).  
  • From 1 May 2023, Lilly is cutting the list price of its non-branded insulin, Insulin Lispro Injection 100 units/mL, to US$25 a vial. This makes it the lowest list-priced mealtime insulin available. 

Furthermore, Lilly launched two plans for easier access to their products for people with diabetes with or without insurance:

  • For people with insurance – Lilly is automatically capping the out-of-pocket costs at US$35 at participating retail pharmacies. 
  • For people without insurance – they can access and download the Lilly Insulin Value Program savings card to receive Lilly insulins for US$35 per month.

Lilly hopes that these aggressive price cuts and their affordability programme will improve access to affordable insulins for all Americans. These cuts follow previous low pricing options adopted by Lilly [2].

Danish multinational pharmaceutical company Novo Nordisk and French drugmaker Sanofi on 14 and 16 March 2023 announced that starting from 1 January 2024 they would slash the price of their insulin drugs by 75% and 78% respectively.

Novo Nordisk is to reduce NovoLog insulin list price by 75%, Levemir and Novolin by 65% for vials and injection pens. NovoLog's list price for five pens to drop to $139.71 from US$558.83, and for a vial, to US$72.34 from US$289.36. Unbranded insulin prices to match respective branded insulin's lowered price.

Sanofi plans to reduce Lantus' price by 78%, limit monthly out-of-pocket expenses to US$35 for privately insured individuals, and decrease Apidra's list price by 70%. The company already offers a US$35 monthly cap on insulin for uninsured diabetes patients.

In late March 2022, the Affordable Insulin Now Act was passed to cap monthly insulin costs at US$35 to benefit both Medicare patients and those on minimalistic insurance plans [3]. 

These massive price cutting moves of major insulin pharmaceutical companies come after the Inflation Reduction Act signed by President Joe Biden on 16 August 2022 which capped monthly insulin costs for Medicare beneficiaries at US$35, but it did not provide protection to diabetes patients who are covered by private insurance.

About 37 million people in the US (11.3% of the population) have diabetes, and 8.4 million of them depend on insulin, as per the CDC and the American Diabetes Association.

Related articles
FDA approves adalimumab and insulin glargine biosimilars Yusimry and Rezvoglar

British Columbia expands biosimilar switching programme to include insulin 

FDA opens pathway to biosimilar insulin products

Comments criticize FDA guidance on insulin biosimilars

The new section of the ‘Latin American Forum’ on GaBI has been launched. The objective of this new section is to provide you with all the latest news and updates on developments of generic and biosimilar medicines in Latin America in Spanish.

View the latest headline article: La adopción exitosa de biosimilares en Europa y EE. UU.

Browse the news in the Latin American Forum!

Register to receive the GaBI Latin American Forum newsletter. Inform colleagues and friends of this new initiative.

Se ha lanzado la nueva sección del ‘Foro Latinoamericano’ sobre GaBI. El objetivo de esta nueva sección es brindarle las últimas noticias y actualizaciones sobre desarrollos de medicamentos genéricos y biosimilares en América Latina en español.

Ver el último artículo de cabecera: La adopción exitosa de biosimilares en Europa y EE. UU.

!Explore las noticias en el Foro Latinoamericano!

Regístrese para recibir el boletín informativo GaBI Foro Latinoamericano. Informe a colegas y amigos sobre esta nueva iniciativa. 


1.  GaBI Online - Generics and Biosimilars Initiative. New insulin glargine and potential adalimumab interchangeable biosimilars[]. Mol, Belgium: Pro Pharma Communications International; [cited 2023 Mar 23]. Available from:
2. GaBI Online - Generics and Biosimilars Initiative. Eli Lilly and Novo Nordisk launches lower-priced insulin options[]. Mol, Belgium: Pro Pharma Communications International; [cited 2023 Mar 23]. Available from:
3. GaBI Online - Generics and Biosimilars Initiative. United States legislation to improve access to insulin []. Mol, Belgium: Pro Pharma Communications International; [cited 2023 Mar 23]. Available from:

Permission granted to reproduce for personal and non-commercial use only. All other reproduction, copy or reprinting of all or part of any ‘Content’ found on this website is strictly prohibited without the prior consent of the publisher. Contact the publisher to obtain permission before redistributing.

Copyright – Unless otherwise stated all contents of this website are © 2023 Pro Pharma Communications International. All Rights Reserved.

comment icon Comments (0)
Post your comment
Most viewed articles
Sobre GaBI
INICIO/Sobre GaBI Posted 06/08/2009
EU guidelines for biosimilars
EMA logo 1 V13C15
INICIO/Directrices Posted 08/10/2010