Biosimilars: a new challenge in the current pharmacology

Biosimilares/Investigación | Posted 25/03/2016 post-comment0 Post your comment

In a review of biosimilars in rheumatology author José M Serra López-Matencio and colleagues from the Universidad Autónoma, Madrid, Spain discuss issues surrounding biosimilars*.

Pharmacology MIT

The biological market is constantly growing. These drugs have experienced huge advances in dealing with many different diseases such as rheumatoid arthritis (RA), diabetes or cancer and it is hoped that they will continue doing so. Such benefits, however, also come with increased treatment costs, therefore, challenging the access and sustainability of health systems. When biologicals licenses have expired, biosimilars may be approved, lowering prices and increasing access to these drugs.

Nowadays, the biosimilars market is small, representing 3% in 2010 with respect to the sales of the reference biological (somatotropin, epoetin and filgrastim) and only 0.7% of the total pharmaceutical market. However, following patent expiry of drugs such as infliximab, adalimumab, etanercept, rituximab, cetuximab, trastuzumab and bevacizumab, the biosimilar market is expected to grow [1]. In Europe, it is expected that biosimilars will cut prices by 20‒30% in comparison with the reference biologicals, which will also reduce its price in order to remain competitive. This has already happened with filgrastim or epoetin, whose prices have dropped by 40% in the last few years.

In view of these circumstances, it is a priority that all players involved in the use of biological drugs to familarize with these drugs.

A more detailed discussion of the issues surrounding biosimilars is presented in a series of four articles.

*Acknowledgement
This article is prepared based on the paper entitled ‘Biosimilars: a new challenge in the current pharmacology’ by Serra-Matencio JM, Ramirez-Herraiz E, Morell-Baladron A, Castañeda S.Hospital de La Princesa, IIS-IP, Madrid, Universidad Autónoma, Madrid, Spain.

Editor’s comment
Readers interested to learn more about biosimilars are invited to visit www.gabi-journal.net to view the following manuscript published in GaBI Journal:

Product naming, pricing, and market uptake of biosimilars

Readers interested in contributing a research or perspective paper to GaBI Journal – an independent, peer reviewed academic journal – please send us your submission here.

Related Articles
Biosimilars: the clinical perspective

Biosimilars: management of clinical issues

European regulatory pathways for biosimilars

Biologicals: characteristics that make them unique and special

Reference
1. GaBI Online - Generics and Biosimilars Initiative. Biologicals patent expiries [www.gabionline.net]. Mol, Belgium: Pro Pharma Communications International; [cited 2016 Mar 25]. Available from: www.gabionline.net/Biosimilars/General/Biologicals-patent-expiries

Permission granted to reproduce for personal and non-commercial use only. All other reproduction, copy or reprinting of all or part of any ‘Content’ found on this website is strictly prohibited without the prior consent of the publisher. Contact the publisher to obtain permission before redistributing.

Copyright – Unless otherwise stated all contents of this website are © 2016 Pro PharmaCommunications International. All Rights Reserved.

comment icon Comments (0)
Post your comment
Most viewed articles
Sobre GaBI
INICIO/Sobre GaBI Posted 06/08/2009
EU guidelines for biosimilars
EMA logo 1 V13C15
INICIO/Directrices Posted 08/10/2010