Plavix (clopidogrel bisulfate), which prevents blood clots in patients at risk of heart attack or stroke and is the world's second biggest-selling prescription drug, loses US patent protection in November 2011. Bristol-Myers Squibb markets the drug in the US, while its partner sanofi-aventis sells it in other countries. Bristol-Myers got almost a third of its 2009 revenue from Plavix—Euros 4.6 billion out of a total of Euros 14.1 billion—and is racing to find new drugs to fill the gap.
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Generics
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Biosimilars
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General
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