Alvotech began construction on the purpose-built plant in the science park of the University of Iceland in Reykjavik back in November 2013 [1]. Iceland was chosen as a logical place for Alvogen’s biosimilars business, due to its favourable environment with a strong regulatory system, low operating costs, a great talent pool, high quality standards and a convenient geographical location between the European Union and the US that is within easy reach of the rest of the world. The new facility is expected to create around 200 jobs and will include 12 disposable bioreactors, along with filling and finishing capabilities for syringes and vials.

On 13 February 2014, Alvogen launched the infliximab biosimilar Inflectra in Central and Eastern Europe in collaboration with Hospira [2]. The company also has six of its own biosimilars in development and is investing over US$500 million in the development of its pipeline and its new development and manufacturing plant.

The company’s own biosimilars include versions of leading monoclonal antibody molecules, some of which are reported to be at an advanced development stage. Alvotech intends to bring the biosimilars to market by 2018.

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References
1. GaBI Online - Generics and Biosimilars Initiative. Alvotech invests US$250 million in biosimilars [www.gabionline.net]. Mol, Belgium: Pro Pharma Communications International; [cited 2016 Jun 17]. Available from: www.gabionline.net/Biosimilars/News/Alvotech-invests-US-250-million-in-biosimilars
2. GaBI Online - Generics and Biosimilars Initiative. Alvogen launches infliximab biosimilar in Europe [www.gabionline.net]. Mol, Belgium: Pro Pharma Communications International; [cited 2016 Jun 17]. Available from: www.gabionline.net/Biosimilars/News/Alvogen-launches-infliximab-biosimilar-in-Europe

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