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Momenta to reduce its biosimilars programmes Posted 26/10/2018

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US-based biotechnology firm Momenta Pharmaceuticals (Momenta) announced on 1 October 2018 that it would be focusing on two key biosimilars and quit the development of five others.

The company says that it will focusing on its two late-stage biosimilar assets. These include its wholly-owned candidate adalimumab biosimilar, M923; and M710, its candidate aflibercept biosimilar which is being developed in collaboration with Mylan.

Momenta made a deal with US generics giant Mylan back in 2016 for six biosimilars, which included a candidate abatacept biosimilar, M834, as well as the candidate aflibercept biosimilar, M710 [1]. However, the company now says that it ‘has initiated discussions’ with Mylan ‘to exit its participation in the development of its other five biosimilar program[me]s including M834’.

The decision says Momenta is ‘aimed at reducing costs of biosimilar development and focusing the company’s resources on its pipeline of novel drug candidates for immune-mediated diseases’.

Momenta and Mylan are currently carrying out a phase III trial for M710 in subjects with diabetic macular oedema [2]. Momenta also reported positive results from a phase III trial of M923 in November 2016 [3].

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References
1. GaBI Online - Generics and Biosimilars Initiative. Mylan and Momenta to jointly develop and commercialize six biosimilar products [www.gabionline.net]. Mol, Belgium: Pro Pharma Communications International; [cited 2018 Oct 26]. Available from: www.gabionline.net/Pharma-News/Mylan-and-Momenta-to-jointly-develop-and-commercialize-six-biosimilar-products
2. GaBI Online - Generics and Biosimilars Initiative. Mylan/Momenta announce development strategy for aflibercept biosimilar [www.gabionline.net]. Mol, Belgium: Pro Pharma Communications International; [cited 2018 Oct 26]. Available from: www.gabionline.net/Biosimilars/General/Mylan-Momenta-announce-development-strategy-for-aflibercept-biosimilar
3. GaBI Online - Generics and Biosimilars Initiative. Positive phase III results for adalimumab and trastuzumab biosimilars [www.gabionline.net]. Mol, Belgium: Pro Pharma Communications International; [cited 2018 Oct 26]. Available from: www.gabionline.net/Biosimilars/Research/Positive-phase-III-results-for-adalimumab-and-trastuzumab-biosimilars

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Source: Momenta

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