This variation is mostly attributed to differences in the healthcare systems between different countries. In some countries this can mean that therapy costs may not always have reduced after the introduction of biosimilars, see Figure 1.

Therapy costs in Europe in 2013 compared to 2006 have shown changes of -75% for EPO in Croatia to an incredible 600% increase in the cost of G-CSF therapy in Romania. In fact, despite Eastern European countries leading the way in biosimilars penetration, they have experienced some of the largest relative increases in the cost of biologicals therapy across Europe.

Editor’s Comment
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Reference
1. Rickwood S. Perspectives on the evolving biosimilars landscape. 13th EGA-European Biosimilars Group Conference; 23–24 April 2015; London, UK.

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