Biosimilars education still needed for US and EU clinicians Posted 10/05/2019

A review of the literature has concluded that healthcare providers are still cautious when it comes to biosimilars and that clinician-directed education is still needed to increase biosimilar knowledge, facilitate prescribing changes and increase use of biosimilars [1].

Author Leonard and colleagues carried out a literature search using journal databases, including PubMed, Embase and the Cochrane Library, using terms related to biosimilars, survey questionnaires and education. Twenty healthcare provider surveys (3 US and 17 European) published between January 2014 and March 2018 met the inclusion criteria and were abstracted for data related to providers’ biosimilar prescribing habits, knowledge, safety and efficacy concerns, extrapolation and interchangeability viewpoints, and exposure to biosimilar educational activities.

The results of the review showed that most of the reviewed studies primarily surveyed gastroenterologists, rheumatologists and specialty physicians who routinely prescribed originator biologicals. It also showed that the percentage of biosimilar prescribing varied widely between countries and within similar practice fields.

The review noted that both US and European clinicians seemed to be unaware of the existence of biosimilars as alternative safe and effective treatment options for their patients. Most physicians perceived biosimilars as second- or third-line treatment options in patients requiring biological therapy and restricted use to biological treatment-naïve patients only. This was accompanied by concerns about biosimilar safety, efficacy, extrapolation and interchangeability.

The review also identified gaps in biosimilar knowledge and understanding among clinicians. The majority of surveyed physicians indicated having an incomplete or basic awareness of biosimilars, with familiarity higher among hospital-based rather than office-based practitioners.

Finally, detailed descriptions of biosimilar education programmes were lacking within the literature. Self-instruction and independent guideline and/or journal article review were the most common learning methods, followed by colleague discussion, continuing education, and consulting promotional manufacturer materials.

The authors concluded that ‘findings from this review indicate that US and European healthcare providers still approach biosimilar medicines with caution, citing limited biosimilar knowledge, low prescribing comfort, and safety and efficacy concerns as main deterrents for biosimilar use’. The authors say that ‘to realize the full cost-saving potential of biosimilar medicines, clinician-directed biosimilar education will be imperative to address gaps in biosimilar knowledge, facilitate prescribing changes, and ultimately increase biosimilar use’.

Conflict of interest
The authors of the research paper [1] declared that there was no conflict of interest.

Related articles
ESMO survey highlights need for education and alignment

Clinician biosimilar prescribing habits and need for education

Reference
1. Leonard E, Wascovich M, Oskouei S, et at. Factors affecting health care provider knowledge and acceptance of biosimilar medicines: a systematic review. J Manag Care Spec Pharm. 2019;25(1):102-12.

Permission granted to reproduce for personal and non-commercial use only. All other reproduction, copy or reprinting of all or part of any ‘Content’ found on this website is strictly prohibited without the prior consent of the publisher. Contact the publisher to obtain permission before redistributing.

Copyright – Unless otherwise stated all contents of this website are © 2019 Pro Pharma Communications International. All Rights Reserved.

Comments (0)